IUNI has over 165 faculty affiliates from across IU. You may browse through listings below – clicking on a name will expand to show you full listings. You may also search through keywords and biographies in the search bar below.
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|Macklin, Paul||Intelligent Systems Engineering, School of Informatics and Computing / Bloomington|
Bio: I work in the newly-formed Department of Intelligent Systems Engineering, where I am helping to start the bioengineering track. My work involves developing sophisticated, multiscale models of tissues and organisms that show dynamical cross-talk and feedbacks between networks at multiple scales: genetics, epigenetics, RNA transcription, protein dynamics, cell phenotype, cell and tissue mechanics, multicellular communications through chemical and mechanical signals, tissue remodeling, networked physiologic subsystems (e.g., immune system, cardiovascular system, etc.), organism-scale health/behavior, and the epidemiologic scale that emerges from the distribution of individual traits. Most of my prior work has focused on cancer and tissue biology, and I am now expanding to other areas such as cognitive health. I have developed and maintain several open source packages for simulation investigations of these dynamical multiscale systems, and I also lead an international group in creating a data standard / data model for these problems.